Table 1. Red Blood Cell Parameters of the Cornus mas Fruit Extract-Treated Rats a,b.
Parameter/Group | Control (Normal) | Control (Placebo) | C. mas (50 mg/kg BW) | C. mas (200 mg/kg BW) | C. mas (400 mg/kg BW) | P Value |
---|---|---|---|---|---|---|
RBC, 1012/L | 7.8 ± 0.6 | 7.8 ± 0.6 | 7.6 ± 0.3 | 7.7 ± 0.4 | 7.9 ± 0.5 | 0.582 |
Hb, g/dL | 13.0 ± 0.5 | 13.1 ± 0.8 | 13.1 ± 0.9 | 12.9 ± 0.4 | 13.5 ± 0.9 | 0.407 |
PCV, % | 45.6 ± 2.1 | 45.4 ± 2.1 | 44.1 ± 2.1 | 43.4 ± 2.0 | 46.3 ± 5.6 | 0.364 |
MCV, fL | 58.1 ± 2.3 | 58.0 ± 2.4 | 58.6 ± 2.6 | 56.4 ± 1.5 | 56.7 ± 1.7 | 0.163 |
MCH, pg | 16.6 ± 0.9 | 16.6 ± 0.8 | 17.3 ± 0.9 | 16.8 ± 0.7 | 17.2 ± 0.5 | 0.339 |
MCHC, g/dL | 28.6 ± 0.6 | 28.8 ± 0.9 | 29.6 ± 1.3 | 29.7 ± 1.3 | 30.3 ± 0.8 | 0.047 |
RDW, % | 14.7 ± 1.3 | 14.7 ± 0.9 | 13.9 ± 0.7 | 13.9 ± 0.5 | 13.8 ± 0.4 | 0.048 |
HDW, g/dL | 2.5 ± 0.2 | 2.5 ± 0.2 | 2.3 ± 0.1 | 2.3 ± 0.2 | 2.3 ± 0.1 | 0.049 |
a Data are expressed as mean ± SD, the parameters with significant differences (P < 0.05).
b Abbreviations: Hb, hemoglobin; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV; mean corpuscular volume; RBC, red blood cell count; PCV, packed cell volume; RDW, red cell distribution width.