TABLE 1.
Population observed | AVI/AVI | AVI/PAV | PAV/PAV | Total |
---|---|---|---|---|
Patients | 26 (37) | 38 (54) | 6 (8.5) | 70 |
Comparison group | 100 (29) | 177 (51) | 70 (20) | 347 |
Values are n(%) except where indicated. The frequency of PAV/PAV genotype was significantly lower than expected, whereas the AVI/AVI genotype was significantly higher than expected based on comparison population (χ2(2) = 6.526, p = 0.0383).
AVI = alanine, valine, and isoleucine; PAV = proline, alanine, and valine.