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. Author manuscript; available in PMC: 2014 Jul 5.
Published in final edited form as: Int J Low Extrem Wounds. 2011 Aug 19;10(3):122–129. doi: 10.1177/1534734611418157

Fig. 2. Sequence of time-dependent epiboly in the bilayered skin construct (BSC) in vitro.

Fig. 2

By 72 hours, the BSC has undergone fully epiboly, as evidenced by the migration of the original epidermis of the construct to completely envelop the BSC dermal component. The very margins of the epibolized (inferior) epidermal component show early evidence of acanthosis and stratum corneum formation, while the middle has not yet differentiated and has not yet formed a stratum corneum. 20×.