. 2014 Feb 14;36(3):9627. doi: 10.1007/s11357-014-9627-2

Table 4.

Model analysis of rs17105278 T>C and rs4902566 C>T genotypes in the NEI sample set

		Genotype	Control	AMD	P/P _a	OR (95 % CI)	FDR P
		Genotype	N (%)		P/P _a	OR (95 % CI)	FDR P
Dominant model	rs17105278 T>C	TT	80 (46.2)	84 (33.7)	9.53 × 10⁻³	1.69 (1.135–2.516)	0.02
	rs17105278 T>C	TC+CC	93 (53.8)	165 (66.3)	9.53 × 10⁻³	1.69 (1.135–2.516)	0.02
	rs4902566 C>T	CC	102 (57.6)	101 (40.7)	5.84 × 10⁻⁴	1.98 (1.339–2.927)	1.56 × 10⁻³
	rs4902566 C>T	CT+TT	75 (42.4)	147 (59.3)	5.84 × 10⁻⁴	1.98 (1.339–2.927)	1.56 × 10⁻³
Recessive model	rs17105278 T>C	TT+TC	152 (87.9)	189 (75.9)	2.16 × 10⁻³	2.30 (1.35–3.95)	4.32 × 10⁻³
	rs17105278 T>C	CC	21 (12.1)	60 (24.1)	2.16 × 10⁻³	2.30 (1.35–3.95)	4.32 × 10⁻³
	rs4902566 C>T	CC+CT	166 (93.8)	194 (78.2)	1.12 × 10⁻⁵	4.20 (2.13–8.26)	8.93 × 10⁻⁵
	rs4902566 C>T	TT	11 (6.2)	54 (21.8)	1.12 × 10⁻⁵	4.20 (2.13–8.26)	8.93 × 10⁻⁵

P values are adjusted for age, gender, and smoking status (P _a); FDR false discovery rate to adjust for multiple testing