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. 2014 Jun 25;7:39. doi: 10.1186/1755-8794-7-39

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Copyright © 2014 Markunas et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Weighted PCA plots for integrative sparse k-means clustering. Each point represents a patient and each class of patients is shown in a different color (blue, red, or green). (A) Dura-Cranial (Proportion of variance explained by PC1 (0.39) and PC2 (0.16)), (B) Blood-Cranial (Proportion of variance explained by PC1 (0.62) and PC2 (0.24)), and (C) Blood-Dura-Cranial integrative sparse k-means clustering analysis (Proportion of variance explained by PC1 (0.40) and PC2 (0.17)). The “true” patient class is unknown and is based on the sparse k-means clustering assignment.