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. Author manuscript; available in PMC: 2014 Jul 5.

Published in final edited form as: Health (Irvine Calif). 2013 Oct;5(10B):14–28. doi: 10.4236/health.2013.510A2003

Effect of Polymyxin B (PMB, an ENX inhibitor) at 10 mg/ml on the induction IL-6 (A) and IL-8 (B) in BEAS-2B exposed to PM₁₀ (ADEPRC) extracts for 24 h. Cells were treated with PM₁₀ ADEPRC extracts in the presence (w PMB) and absence of PMB (w/o PMB) and cytokine induction was measured. LPS (10 mg/ml) was used as a positive control. Bars represent mean IL-8 concentration ± SEM. Stars over the bars indicate comparison of a treatment with DMSO. Stars over the line indicate a comparison between two treatments. All samples were tested in three independent experiments; ***p < 0.001, **p < 0.01, *p < 0.05.

Effect of Polymyxin B (PMB, an ENX inhibitor) at 10 mg/ml on the induction IL-6 (A) and IL-8 (B) in BEAS-2B exposed to PM₁₀ (ADEPRC) extracts for 24 h. Cells were treated with PM₁₀ ADEPRC extracts in the presence (w PMB) and absence of PMB (w/o PMB) and cytokine induction was measured. LPS (10 mg/ml) was used as a positive control. Bars represent mean IL-8 concentration ± SEM. Stars over the bars indicate comparison of a treatment with DMSO. Stars over the line indicate a comparison between two treatments. All samples were tested in three independent experiments; ***p < 0.001, **p < 0.01, *p < 0.05.