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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Inflamm Bowel Dis. 2013 Sep;19(10):2041–2050. doi: 10.1097/MIB.0b013e318295fd8f

Figure 3. Radiation-induced colitis in WKO mice is not dependent on the presence of Helicobacter spp.

Figure 3

(a) Mean percent of initial weights ± SEM of sublethally irradiated and non-irradiated WKO mice in SPF and Helicobacter spp.-free conditions over 9 weeks after irradiation starting at 2 months of age. (b) Mean histologic colitis indices ± SEM in sublethally irradiated or non-irradiated Helicobacter spp.-free or SPF WKO mice. Data were pooled from five independent experiments (n = 22 for each irradiated group; n = 15 for non-irr H-free; n = 8 for non-irr SPF). Kruskal-Wallis analysis with post-hoc Dunn’s test showed * p < 0.05. (c) Representative H&E images of non-irradiated (left) and irradiated (middle) Helicobacter spp.-free WKO mice and irradiated SPF WKO (right), 10x objective. H-free = Helicobacter spp.-free; Irr = irradiated.