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. 2014 Mar 26;8(5):956–967. doi: 10.1016/j.molonc.2014.03.005

Figure 4.

Figure 4

SW IV‐134 activates the NF‐қB pathway and TNFα dependent apoptosis. (A) Western blot of PANC‐1 cells treated with DMSO as control and SW IV‐134 in different time points and concentrations. (B) Caspase‐8 assay PANC‐1 cells treated with and without anti‐TNFα antibody for 1 h, followed by 24 h incubation with SW IV‐134. Activated caspase‐8 was monitored as a surrogate for TNFα induction, *p < 0.05.