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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Trends Mol Med. 2014 Apr 3;20(7):385–393. doi: 10.1016/j.molmed.2014.03.002

Table 1.

Characteristics of different EV types

Exosomes Microvesicles Apoptotic bodies
Intracellular origin Multivesicular bodies Plasma membrane Plasma membrane
Size 40–150 nm 50–2000 nm 50–5000 nm
Suggested markers ALIX, TSG101, tetraspanins Unknown DNA, histones
Density 1.13–1.19 g/cm3 Unknown 1.16–1.28 g/cm3
Appearance in transmission electron microscopy Cup-shaped Heterogeneous Heterogeneous
Refs [6, 84, 85] [84, 86] [87, 88]