Table 1.
Exosomes | Microvesicles | Apoptotic bodies | |
---|---|---|---|
Intracellular origin | Multivesicular bodies | Plasma membrane | Plasma membrane |
Size | 40–150 nm | 50–2000 nm | 50–5000 nm |
Suggested markers | ALIX, TSG101, tetraspanins | Unknown | DNA, histones |
Density | 1.13–1.19 g/cm3 | Unknown | 1.16–1.28 g/cm3 |
Appearance in transmission electron microscopy | Cup-shaped | Heterogeneous | Heterogeneous |
Refs | [6, 84, 85] | [84, 86] | [87, 88] |