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Western blotting was used to compare the levels of VEGFR2 protein induced by VEGF gene silencing among the three groups of HUVECs. The protein expression of pVEGFR2 was sharply increased in hypoxic culture at 3, 6, 12, and 24 h in the control, mock and experimental groups. **p < 0.01 versus 3H protein expression, ##p < 0.01 versus 6H protein expression, &&p < 0.01 versus 12H protein expression
