Figure 5.
β-cell cytotoxicity of 8.3-CTLs from 8.3-NOD.PO+/– and 8.3-NOD.PO–/– mice. NRP-differentiated 8.3-CTLs were tested in cytotoxicity assays against islet cells from NOD/Lt, C57BL/6, and NOD.lpr/lpr mice (at a 1:10 target/effector ratio).
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