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NNAV increased the CD4/CD8 T cell ratio in DEX-induced immunosuppressed mice. The DEX-induced immunosuppressed C57BL/6J mice were treated with NNAV for 21 days. Then splenocytes were prepared and stained with CD3e-PE-cy5, CD4-PE, and CD8a-FITC for analysis with flow cytometer. The percentage of CD3+CD4+T-cell (a) and CD3+CD8+T-cell (b) and the ratio of the two (c) are shown. Data represent mean values ± SD for 8 mice per group. *P < 0.05 (versus model); # P < 0.05 (versus normal).
