Figure 3.

Effect of S. aureus-derived PAMPs on SEB-induced T cell proliferation in vitro. Splenic mononuclear cells from HLA-DR3 transgenic mice were cultured with indicated concentrations of SEB in the presence or absence of HKSA, 10⁸ bacteria/mL (a), or PGN (b). T cell proliferation was determined by thymidine incorporation. *P < 0.05 compared to cells cultured without HKSA or PGN within that group. Each bar represents mean ± SE from triplicate wells. Representative data from one out of 3 similar experiments are given.