TABLE 3.
Medications Over Time in Adolescents With Bipolar Disorder Receiving Pharmacotherapy With Either Family-Focused Treatment or Enhanced Carea
| Baseline Assessment |
12-Month Assessment |
24-Month Assessment |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Medication | Family-Focused Treatment (N=72) |
Enhanced Care (N=73) |
Family-Focused Treatment (N=49) |
Enhanced Care (N=52) |
Family-Focused Treatment (N=26) |
Enhanced Care (N=31) |
||||||
| N | % | N | % | N | % | N | % | N | % | N | % | |
| Lithium | 15 | 21 | 11 | 15 | 14 | 29 | 12 | 23 | 5 | 19 | 9 | 29 |
| Anticonvulsant | 23 | 32 | 21 | 29 | 21 | 43 | 25 | 48 | 12 | 46 | 14 | 45 |
| Antipsychotic | 58 | 81 | 58 | 79 | 41 | 84 | 42 | 81 | 20 | 77 | 25 | 81 |
| Antidepressant | 21 | 29 | 12 | 16 | 10 | 20 | 9 | 17 | 8 | 31 | 4 | 13 |
| Psychostimulant | 13 | 18 | 10 | 14 | 11 | 22 | 10 | 19 | 6 | 23 | 5 | 16 |
| Anxiolytic | 2 | 3 | 0 | 0 | 3 | 6 | 0 | 0 | 2 | 8 | 1 | 3 |
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of medications | 2.0 | 1.0 | 1.6 | 0.9 | 2.1 | 1.0 | 2.0 | 0.9 | 2.2 | 1.1 | 2.0 | 1.1 |
a
Antipsychotics included both first- and second-generation agents. Anticonvulsants included valproate, lamotrigine, carbamazepine, oxcarbazepine, and topiramate. There were no differences between the treatment groups or treatment-by-time interactions in the proportion of patients taking each medication or in the mean number of medications per patient.