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. Author manuscript; available in PMC: 2015 Aug 15.
Published in final edited form as: Behav Brain Res. 2014 May 27;0:277–286. doi: 10.1016/j.bbr.2014.05.041

Table 1.

Number of c-Fos immunopositive cells (mean ± SE) following social defeat training.

Brain Region 1 Day 7 Day 14 Day Controls
Dominant (N = 8–13) Subordinate (N = 8–12) Dominant (N = 7–12) Subordinate (N = 9–13) Dominant (N = 7–13) Subordinate (N = 7–11) Social Experience (N = 7–11) Handled (N = 8–11)
BLA 16.7 ± 1.3* 23.2 ± 1.3 10.5 ± 1.2 11.6 ± 1.5 17.5 ± 2.4* 10.8 ± 1.9 15.1 ± 2.1 17.9 ± 3.0
dLS 20.6 ± 5.2 22.1 ± 2.1 21.8 ± 4.6 16.7 ± 3.6 35.1 ± 4.8** 27.7 ± 4.5** 28.5 ± 7.6 20.6 ± 4.2
vLS 56.6 ± 10.5 80.2 ± 14.7 55.5 ± 7.7 52.9 ± 10.7 92.7 ± 16.9 71.3 ± 11.2 59.0 ± 10.5^ 24.6 ± 4.0
MPOA 25.4 ± 6.2 40.3 ± 6.5 31.0 ± 6.4 28.1 ± 4.7 34.1 ± 4.7 32.5 ± 6.5 28.2 ± 8.8^ 11.6 ± 1.9
PVN 56.9 ± 11.6 74.5 ± 12.2 68.7 ± 15.6 35.2 ± 7.4 85.3 ± 20.2 79.3 ± 26.9 59.9 ± 7.9^ 25.8 ± 6.1

Note: Sample sizes vary because some individuals were excluded from data analysis due to poor tissue quality.

*

indicates that 1-day and 14-day dominants significantly differed from 1-day and 14-day subordinates, respectively (p < .05).

**

indicates that animals paired for 14 days significantly differed from animals paired for 1 or 7 days (p < .05).

^

indicates a significant difference compared to corresponding handled controls (p < .05). BLA – basolateral amygdala, dLS – dorsal lateral septum, vLS – ventral lateral septum, MPOA – medial preoptic area, PVN – paraventricular nucleus of the hypothalamus.