Table 3.
SNP | Gene | EA-only HR (95% CI)a | Full Cohort HR (95% CI)a | EA-only Pb | Full Cohort P |
---|---|---|---|---|---|
rs833069 | VEGFA | 0.25 (0.105–0.609) | 0.37 (0.211–0.659) | 0.0021 | 7.03×10−4 |
rs2758331 | SOD2 | 0.29 (0.133–0.636) | 0.52 (0.304–0.900) | 0.0019 | 0.019 |
CI = Confidence Interval. EA = European Ancestry, non-Hispanic. HR = Hazard Ratio from survival analyses.
HR and 95% CI were calculated using Cox proportional hazards methods for the outcome of long-term survival, adjusting for the covariates listed in the methods.
Analyses performed on the majority genetic ancestry group (EA) of the cohort (n=273 subjects), using analysis methods outlined in a.