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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Neurobiol Dis. 2014 Mar 29;67:79–87. doi: 10.1016/j.nbd.2014.03.011

Figure 2.

Figure 2

A potential interaction between IPMK and pAMPK. A) Mice fed a 60% HFD for 17 days show a gradual decrease in IPMK while the levels of pAMPK increase (means + SEM). B-C) When pAMPK is induced either by overexpression of catalytic subunit of AMPK in differentiated PC12 cells or by a pharmacological reagent, IPMK levels are decreased. D) Differentiated PC12 cells overexpressed with either myc or IPMK-myc were treated with 100nM insulin for various time points. Overexpression of IPMK further sensitizes insulin-mediated-activation of pAkt. (* p < 0.05)