Fig. 6.

Functional protein interaction network analysis based on the STRING database. The image illustrates a network analysis of sumoylated proteins that was created with STRING. Proteins isolated from mitotic phase, interphase or both were highlighted in red, green or white, respectively. The protein complexes and pathways highlighted by red circle are involved in: (1) ribosome assembly and translation; (2) proteasomal degradation; (3) DNA replication and repair; (4) chromatin remodeling and transcriptional regulation; (5) cell cycle regulation; (6) the mitochondrial respiratory chain; (7) metabolic regulation; and (8) the sumoylation pathway.