Fig. 6.

OHPro and collagen kinetics. A, fraction of newly synthesized OHPro present in protein extracts from control and bleomycin-induced fibrotic lung tissue. B, linear regression analysis of insoluble collagen α-1(I) turnover (LC-MS) and total OHPro turnover (GC-MS). C, absolute OHPro synthesis in pulmonary protein extracts from control and bleomycin-induced fibrotic lung tissue (note log scale). Values are means ± S.D. (n = 3) with statistical comparison between control and treatment groups at each time point (*p < 0.05).