Subcellular localization of FTH1 and its prognostic significance.
A, Cytoplasmic and nuclear staining of FTH1 on TMA and their corresponding cutoff points for Kaplan-Meier analyses; B, Kaplan-Meier analyses show that >75% of tumor cells positive for cFTH1 was associated with favorable prognosis (left panel), whereas >1% positive nFTH1 was related to unfavorable prognosis of TNBC patients (right panel); C, A significant correlation (Spearman correlation) was observed between total FTH1 as measured by LC-MS (5) and cFTH1 staining (left panel), but not nFTH1 staining.