Fig. 7.

Extended olfactory membrane ciliome. A, depicted are all 178 proteins defined as olfactory cilium-specific membrane and membrane-associated proteins as well as 35 further membrane or regulatory proteins with ciliary localization or associated with ciliary functions identified in this work but not defined mature OSN-specific by transcriptome analysis (24). For more details about the proteins, please refer to the text and supplemental Table S1A. Bold, cilium-specific membrane proteins; bold and italic, cilium-specific soluble proteins; regular type, non-cilium-specific proteins. B, components of the olfactory membrane ciliome (dark gray circles) and all other proteins identified in olfactory cilia membrane-enriched fractions (light gray circles) are plotted versus their mean iBAQ value. Relative abundance levels of known proteins of the canonical pathway of olfactory signal transduction (blue circles) including 62 ORs (white circles) and components of the Ca²⁺ signaling network (red circles) are highlighted.