Table I.

Potential clinical applications of oxygen carrying solutions

1– Treatment • Blood substitutes : hemorrhagic shock; hemorrhage (war, surgery); anaemia. • Whole-body rinse out : acute drug intoxication; acute hepaticfailure. • Local ischemia: acute MI; evolving MI; cardiac failure; brain infarction; acute arterial thrombosis and embolism; PTCA ofcoronary artery. • General ischemia: gas embolism; CO intoxication; HAPO;HACO. • Aid for organ recovery : acute renal failure; acute hepatic failure;acute pancreatitis. • Infectious disease : anaerobic and aerobic diseaes;

2- Perfusional protection of organs during surgery – cardiopulmonarybypass, deep hypothermia, circulatory arrest, cardioplegia.

3- Preservation of donor organ.

4- Drug carrier - drug-conjugated haemoglobin and perfluorochemicals.

5- Contrast agent - (Perfluoro-octylbromide)