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. 2014 Jul 7;5:116. doi: 10.3389/fneur.2014.00116

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Copyright © 2014 Irvine, Ferguson, Mitchell, Beattie, Lin, Stuck, Huie, Nielson, Talbott, Inoue, Beattie and Bresnahan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Face, internal, and concurrent validity of the IBB score. (A) Face and internal validity of the IBB score is provided by responsiveness to experimentally graded spinal cord injuries as well as the correlation (inset) with a biomechanical measurement of tissue displacement at the time of contusion injury. Concurrent validity is provided by comparisons with other established outcomes including (B) paw placement, (C) grooming score, and (D) forelimb open field. Insets reflect the scatterplot and regression line between the IBB and each of the established tests. The Pearson correlation (r) and the shared variance (r²) for each appear above the scatterplot; group identity for each point is color coded.