TABLE 2.
EO |
FO |
|||||||
Total EO (n = 59) time effect, P2 | EOI (n = 20) | EOII (n = 20) | EOIII (n = 19) | Total FO (n = 19) time effect, P2 | FOI (n = 10) | FOII (n = 9) | EO vs. FO treatment effect, P3 | |
Females/males | 31/28 | 10/10 | 11/9 | 10/9 | 10/9 | 5/5 | 5/4 | |
BMI group, kg/m2 | 18–25 | 18–25 | >25 | 18–25 | 18–25 | |||
Age group, y | 20–35 | 49–69 | 49–69 | 20–35 | 49–69 | |||
Age, y | 28 ± 2.9b | 59 ± 5.7a | 61 ± 6.3a | 27 ± 2.5b | 60 ± 4.2a | |||
Smokers, % | 35 | 15 | 5 | 20 | 22 | |||
BMI, kg/m2 | 0.007 | 0.17 | 0.71 | |||||
Day 0 | 22.0 ± 2.3b | 23.5 ± 2.4b | 30.1 ± 3.3a | 21.5 ± 2.6b | 24.8 ± 3.1a | |||
Day 56 | 22.2 ± 2.2b | 23.6 ± 2.4b | 30.2 ± 3.3a | 21.5 ± 2.5b | 25.0 ± 3.1a | |||
Body fat, % | 0.001 | 0.19 | 0.43 | |||||
Day 0 | 20.5 ± 5.7b | 25.6 ± 7.7b | 30.6 ± 8.6a | 16.7 ± 6.6b | 28.3 ± 7.0a | |||
Day 56 | 21.0 ± 5.8b* | 25.8 ± 7.5b | 30.9 ± 8.5a | 16.9 ± 6.8b | 28.7 ± 7.2a | |||
Waist circumference, cm | 0.06 | 0.08 | 0.52 | |||||
Day 0 | 80 ± 9.1b | 87 ± 9.2b | 104 ± 6.8a | 77 ± 9.6b | 91 ± 11a | |||
Day 56 | 83 ± 7.3b‡ | 90 ± 6.6b* | 103 ± 8.1a | 84 ± 6.8a* | 89 ± 9.3a | |||
Systolic blood pressure, mm Hg | 0.16 | 0.028 | 0.51 | |||||
Day 0 | 125 ± 10.4c | 135 ± 19.9b | 141 ± 15.6a | 136 ± 13.6a | 136 ± 18.7a | |||
Day 56 | 125 ± 12.3c | 131 ± 16.8b | 137 ± 10.3a | 130 ± 10.3a | 130 ± 18.8a | |||
Diastolic blood pressure, mm Hg | 0.021 | 0.036 | 0.50 | |||||
Day 0 | 82 ± 8.9c | 90 ± 12b | 91 ± 7.9a | 88 ± 7.7a | 88 ± 7.8a | |||
Day 56 | 81 ± 8.4c | 86 ± 10b‡ | 88 ± 9.1a | 84 ± 7.7a‡ | 83 ± 11a |
Values are means ± SDs. *and ‡indicate differences from day 0 within a subgroup (repeated-measures ANOVA; *P ≤ 0.05, ‡0.05 < P ≤ 0.10). Within an oil treatment, means within a row without a common superscript letter differ (multivariate ANOVA; P ≤ 0.05). EO, echium oil; EOI, participants aged 20–35 y with BMI = 18–25 kg/m2, treated with EO; EOII, participants aged 49–69 y with BMI = 18–25 kg/m2, treated with EO; EOIII, participants aged 49–69 y with BMI > 25 kg/m2 and markers of metabolic syndrome or with BMI ≥ 30 kg/m2, treated with EO; FO, fish oil; FOI, participants aged 20–35 y with BMI = 18–25 kg/m2, treated with FO; FOII, participants aged 49–69 y with BMI = 18–25 kg/m2, treated with FO.
Adjusted mean not shown; P value is for effect over time within an oil treatment of total participants (repeated-measures ANCOVA; sex, age, BMI).
Adjusted mean not shown; P value is for the difference between oil treatments of total participants at day 56 (univariate ANCOVA; sex, age, BMI, baseline value).