Table 1.
Tumor markers included in the study and their major functions.
| Biological marker | Functions | Clone | Species | Dilution | Antigen retrieval | Source |
|---|---|---|---|---|---|---|
| LRIG3 | Unclear (receptor regulation?) | LRIG3-207 | Rabbit | 1.50 | CC2pH6 | H Hedman Umeå University, Sweden |
| p53 | Tumor suppression, apoptosis | M7001 | Mouse | 1:1000 | HIER pH6 | DakoCytomation |
| p16 | Tumor suppression | NCL-p16-432 | Mouse | 1:100 | HIER | Novocastra |
| Retinoblastoma protein (Rb) | Tumor suppression | 554136 | Mouse | 1:300 | HIER pH9 | Pharmingen |
| Cytokeratin 10 (CK 10) | Cytoskeleton | MS-611 | Mouse | 1:600 | HIER pH9 | Lab Vision/Neo Markers |
| E-cadherin | Cell-cell adhesion | 13-1700 | Mouse | 1:2500 | HIER pH9 | Zymed |
| C-myc | Cell cycle progression, malignant transformation | 9E11 | Mouse | 1:100 | TED pH 9 DAKO | Novocastra |