Table 2.
Genes meeting the conservative statistical threshold are primarily male biased. Genes with large fold changes are primarily male biased and present on the Y chromosome. Female-biased genes are present on a number of chromosomes and are maximally upregulated at lower levels than those detected in males
| Fold change | GeneName | Description | Chromosome |
|---|---|---|---|
| Up-regulated in Males | |||
| 3604.8 | RPS4Y1 | Ribosomal protein S4, Y-linked 1 | Y |
| 2543.6 | RPS4Y2 | Ribosomal protein S4, Y-linked 2 | Y |
| 109.5 | CYorfl4 | Chromosome Y open reading frame 14 | Y |
| 78.6 | CYorfl5A | Chromosome Y open reading frame 15A | Y |
| 66.0 | AL713714 | mRNA; cDNA DKFZp667C0715 (from clone DKFZp667C0715) | X |
| 44.6 | DDX3Y | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked | Y |
| 37.0 | JARID1D | Jumonji, AT rich interactive domain ID (JARID1D) | Y |
| 32.7 | TTTY15 | Testis-specific transcript, Y-linked 15 | Y |
| 23.1 | CYorfl5B | Lipopolysaccaride-Specific Response 5-Like Protein | Y |
| 20.9 | TTTY2 | Testis-specific transcript, Y-linked 2 | Y |
| 16.0 | USP9Y | Ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila) | Y |
| 13.9 | UTY | Ubiquitously transcribed tetratricopeptide repeat gene, Y-linked, transcript variant 3 | Y |
| 9.4 | TTTY14 | Testis-specific transcript, Y-linked 14 on chromosome Y | Y |
| 9.2 | NLGN4Y | Neuroligin 4, Y-linked | Y |
| 8.1 | EIF1AY | Eukaryotic translation initiation factor 1A, Y-linked | Y |
| 7.7 | ZFY | Zinc finger protein, Y-linked | Y |
| 6.3 | UTY | Ubiquitously transcribed tetratricopeptide repeat gene, Y-linked, transcript variant 1 | Y |
| 5.2 | FLJ43390 | cDNA FU39142 fis, clone OCBBF1000049. | Y |
| 3.2 | AW976081 | EST3SS190 MAGE resequences, MAGN Homo sapiens cDNA | 7 |
| 3.2 | ZSCAN4 | Zinc finger and SCAN domain containing 4 | 19 |
| 3.0 | PRKY | Protein kinase, Y-linked | Y |
| 2.9 | ALOX12P2 | Arachidonate 12-lipoxygenase pseudogene 2 | 17 |
| 2.8 | BX094246 | Soares testis NHTcDNA clone | 4 |
| 2.5 | SV2B | Synaptic vesicle glycoprotein 2B | 15 |
| 2.3 | THC2674900 | Unknown | 6 |
| 2.3 | PTPRG | Protein tyrosine phosphatase, receptor type, G | 3 |
| 2.3 | CYP1A2 | Cytochrome P450, family 1, subfamily A, polypeptide 2 | 15 |
| 2.2 | THC2621536 | Unknown | 1 |
| 2.1 | KLHL34 | Kelch-like 34 (Drosophila) | X |
| 2.0 | COL10A1 | Collagen, type X, alpha KSchmid metaphyseal chondrodysplasia) | 6 |
| Up-regulated in Females | |||
| 17.7 | XIST | X (inactive)-specific transcript (XIST) | X |
| 3.2 | ARSD | Arylsulfatase D, transcript variant 2 | X |
| 2.7 | TSPAN13 | Tetraspanin 13 | 7 |
| 2.6 | CHST2 | Carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 3 |
| 2.1 | PEX7 | Peroxisomal biogenesis factor 7 | 6 |
| 2.1 | TXNDC12 | Thioredoxin domain containing 12 | 1 |