Figure 3.

Pharmacology of the ventral noradrenergic bundle-stimulated O₂ response recorded in the ventral bed nucleus of the stria terminalis. The substrate inhibited is indicated underneath the data columns. Systemic drug administration (solid) was performed through intraperitoneal injection. Local drug administration (crosshatch) was accomplished through iontophoretic ejection. n=5 for all groups except saline (n=25). Data are reported as a percentage of baseline. Significance was determined by a one-way analysis of variance with a Bonferroni post hoc test comparing drug with its vehicle control (saline or 4-MC). *P<0.05, **P<0.01, ***P<0.001. ABT, 1-aminobenzotriazole; CYP, cytochrome P450; DMI, desipramine; IDA, idazoxan; 4-MC, 4-methylcatechol; LN, L-NAME; NET, norepinephrine transporter; NOS, nitric oxide synthase; PROP, propranolol; TZ, terazosin.