Table 1. Summary of the BBB opening quantification results.

Group	# Of mice	Dextran MW (kDa)	Pressure (MPa)	Fluorescence intensity mean±s.d. ( × 106)	P value(fluorescence intensity>0)	Area of fluorescence mean±s.d. (%)	P value(area of fluorescence>0)	Successful delivery?
1	4	3	0.31	0.01±0.02	0.20	0.75±1.53	0.20	No
2	4	70	0.31	0.06±0.06	0.08	4.57±4.75	0.08	No
3	4	500	0.31	0.01±0.01	0.08	0.64±1.17	0.18	No
4	4	2,000	0.31	−0.01±0.01	0.93	−0.39±0.31	0.95	No
5	4	3	0.51	0.31±0.06	0.00	29.93±5.00	0.00	Yes
6	4	70	0.51	0.28±0.12	0.01	17.15±5.79	0.01	Yes
7	4	500	0.51	0.03±0.04	0.11	2.17±2.70	0.10	No
8	4	2,000	0.51	0.02±0.03	0.10	1.28±1.51	0.09	No
9	4	3	0.84	1.22±0.27	0.00	82.66±9.55	0.00	Yes
10	4	70	0.84	0.29±0.16	0.02	25.55±12.65	0.01	Yes
11	4	500	0.84	0.11±0.05	0.01	8.53±2.09	0.00	Yes
12	4	2,000	0.84	0.05±0.02	0.01	2.23±0.37	0.00	Yes

BBB, blood–brain barrier; MW, molecular weight.