Table 1. Mouse survival after HI in chimeric mice with Nr4a1 −/− or WT hematopoietic system.
| Time of survival assessment | WT → WT | Nr4a1−/− → WT |
|---|---|---|
| 37 minutes HI | ||
| Immediately after hypoxia | n=17/19 (89%) | n=11/19 (58%) |
| 7 d.p.i. | n=16/17 (94%) | n=9/11 (82%) |
| 30 minutes HI | ||
| Immediately after hypoxia | n=5/6 (83%) | n=5/6 (83%) |
| 14 d.p.i. | n=5/5 (100%) | n=5/5 (100%) |
| Sham | ||
| 7 d.p.i. | n=8/8 (100%) | n=11/11 (100%) |
d.p.i., day post injury; HI, hypoxia-ischemia; WT, wild type. Six-month-old Nr4a1−/− → WT and WT → WT mice were subjected to a sham surgery or to HI injury for 37 or 30 minutes. Mouse survival was assessed immediately after hypoxia and up to 7 d.p.i. or 14 d.p.i. (Results are expressed as: live mice/total mice (survival %).