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. Author manuscript; available in PMC: 2014 Jul 7.
Published in final edited form as: Immunol Allergy Clin North Am. 2014 Mar 13;34(2):357–364. doi: 10.1016/j.iac.2014.01.013

Fig. 2.

Fig. 2

Bone marrow biopsy and aspirate in a patient with chronic eosinophilic leukemia carrying the FIP1L1-PDGFRA rearrangement. Increased numbers of hypogranulated neoplastic eosinophils are observed in the aspirate (A, B) (Wright-Giemsa, original magnification ×100). The infiltrate predominantly consists of eosinophils in a background of fibrosis in the biopsy (C, D) (Hematoxylin and Eosin, original magnification ×400) as opposed to mastocytosis whereby the predominant infiltrate is that of mast cells. (Courtesy of German A. Pihan, MD, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.)