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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: J Immunol. 2014 Jun 4;193(1):277–284. doi: 10.4049/jimmunol.1400417

FIGURE 8.

FIGURE 8

NK cell population densities in the FRT mucosa do not correlate with SIVmac239Δnef vaccine protection before or after high dose vaginal challenge. NK cells in the cervical (A) and vaginal (B) mucosa were quantified by IHC in tissues from naïve, SIVmac251 vaginally infected, SIVmac239Δnef-vaccinated, vaccinated plus vaginally challenged rhesus macaques. There was no correlation between NK cell density prior to and after vaginal challenge with protection, and NK cell densities did not increase following challenge in the vaccinated animals. (* = NOT significant-NS). Macrophage recruitment was also inhibited in the vaccinated animals (C).