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. Author manuscript; available in PMC: 2015 Apr 16.
Published in final edited form as: Cochrane Database Syst Rev. 2014 Apr 16;4:CD009868. doi: 10.1002/14651858.CD009868.pub2

Comparison 3. Cholesterol.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Total cholesterol 9 5569 Mean Difference (IV, Random, 95% CI) -0.75 [-1.05, -0.46]
2 LDL cholesterol 8 5365 Mean Difference (IV, Random, 95% CI) -0.81 [-1.09, -0.53]
3 Total cholesterol: primary prevention trials 7 2147 Mean Difference (IV, Random, 95% CI) -0.92 [-1.18, -0.65]
4 Total cholesterol: 3+ drugs only 6 3796 Mean Difference (IV, Random, 95% CI) -0.65 [-1.10, -0.21]
5 Total cholesterol: comparator as usual care 3 3624 Mean Difference (IV, Random, 95% CI) -0.28 [-0.66, 0.10]