Table 1.
Theeffect of SSNX on serum LDH levels, MDA contents and GSH-Px activities after MI/R injury.
| Groups | Dose, mg/kg | LDH, U/L | MDA, nmol/mg protein | GSH-Px, U/mg protein |
|---|---|---|---|---|
| Sham | — | 489 ± 96 | 1.58 ± 0.25 | 29.93 ± 6.11 |
| I/R | — | 1843 ± 787## | 4.55 ± 0.81## | 16.14 ± 2.32## |
| I/R + TMZ | 10 | 911 ± 416∗∗ | 1.89 ± 0.26∗∗ | 24.77 ± 3.91∗ |
| I/R + SSNX | 22.5 | 953 ± 271∗ | 2.32 ± 0.89∗∗ | 22.14 ± 4.47 |
| I/R + SSNX | 45 | 828 ± 301∗∗ | 2.17 ± 0.49∗∗ | 25.10 ± 5.52∗ |
Note: LDH, n = 8/group; MDA, n = 6/group; GSH-Px, n = 6/group; Date are shown as mean ± SD, ## P < 0.01 versus Sham group, ∗P < 0.05, ∗∗P < 0.01 versus I/R group.