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Effects of CDX-4MDM treatment on apoptosis in WT mice exposed to cigarette smoke or ambient air for 20 weeks. Counting of TUNEL positive cells and calculating Apoptosis Index (percentage of cells positively stained in TUNEL assay). Ten random pictures of each animal were examined. N = 5 per group. Air = ambient air exposure. SM = cigarette smoke exposure. Veh = CDX containing vehicle. Tx = CDX-4MDM. * represents analysis by ANOVA, and ** by Bonferroni subgroup comparison.
