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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: J Immunol. 2014 Apr 25;192(11):5059–5068. doi: 10.4049/jimmunol.1400452

Table 3.

Effect of 4MDM on LTA4H aminopeptidase activity.

pH 7.2 pH 6.7 pH 6.7 pH 6.7
4MDM 0.0 µM 0.0 µM 0.8 µM 8.0 µM
kcat1 27.5 ± 1.12 17.2 ± 2.24 59.3 ± 6.10 89.8 ± 6.26
KM2 7.66 ± 0.74 16.30 ± 3.99 14.51 ± 2.69 10.83 ± 1.53
1

kcat = enzymatic turnover (s−1)

2

KM2 = concentration at one-half maximum velocity (mM)