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. 1999 Jun 15;103(12):1677–1684. doi: 10.1172/JCI5645

Figure 3.

Figure 3

Differential effects of cAMP on junctional conductance of CFPAC-1 and PLJ-CFTR cell pairs. Examples of junctional conductances evaluated from a CFPAC-1 (a) and a PLJ-CFTR cell pair (b). Whereas exposure of PLJ-CFTR cells to 10 μM forskolin, 500 μM 8br-cAMP, and 500 μM CPT-cAMP increased their electrical coupling in a reversible manner, the cAMP cocktail (cAMP) was without effect on junctional conductance of the CFPAC-1 cell pair. Bars indicate the duration of drugs superfusion. Dashed lines indicate the zero junctional conductance level.