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. Author manuscript; available in PMC: 2015 Apr 30.
Published in final edited form as: Psychiatry Res. 2014 Feb 19;222(0):52–59. doi: 10.1016/j.pscychresns.2014.02.007

Table 2.

Mean FA values of the whole brain, cerebral, and lobar FA skeletons

SZ group
(n=24)		 HC group
(n=25)
Region Number
of voxels		 Mean
FA		 SD Mean
FA		 SD t
value		 df p (two-
tailed)		 %
reduction
FA skeleton of whole brain (cerebrum, cerebellum, and brain stem) 129382 0.40 0.02 0.42 0.01 2.49 47 0.016*a 2.7
FA skeleton of cerebrum 116182 0.40 0.02 0.41 0.01 2.63 47 0.014*b 2.9
FA skeleton of cerebellum 7315 0.37 0.02 0.38 0.01 1.41 47 0.164 1.9
FA skeleton of brain stem 5885 0.52 0.02 0.53 0.02 0.21 47 0.832 0.4
FA skeleton of cerebrum in left hemisphere 57512 0.40 0.02 0.41 0.01 2.66 47 0.011*c 2.9
FA skeleton of cerebrum in right hemisphere 58670 0.40 0.02 0.41 0.02 2.56 47 0.011*c 2.7
FA skeleton of left frontal lobe 20050 0.38 0.02 0.39 0.01 3.18 47 0.003*d 3.6
FA skeleton of right frontal lobe 20101 0.39 0.02 0.40 0.02 2.95 47 0.005*d 3.2
FA skeleton of left temporal lobe 10758 0.39 0.02 0.40 0.02 2.30 47 0.026*e 2.5
FA skeleton of right temporal lobe 11571 0.39 0.02 0.40 0.02 2.22 47 0.031*e 2.5
FA skeleton of left parietooccipital lobe 17481 0.40 0.02 0.41 0.02 2.54 47 0.015*e 3.2
FA skeleton of right parietooccipital lobe 18014 0.40 0.02 0.41 0.02 2.76 47 0.008*e 3.5
FA skeleton of left subcortical region 9223 0.47 0.02 0.47 0.01 1.04 47 0.306 1.0
FA skeleton of right subcortical region 8984 0.46 0.02 0.47 0.01 1.42 47 0.162 1.4

Abbreviations: FA, fractional anisotropy; SZ, schizophrenia; HC, healthy control subject

a

A two sample t-test with cutoff p value of 0.05 showed significant FA reduction in the schizophrenia compared with the HC.

b

A two sample t-test with a Bonferoni-corrected cutoff p value of 0.017 (0.05/3 regions) showed significant FA reduction in the schizophrenia compared with the HC.

c

A repeated measures analysis of variance, post hoc analysis using simple t-test with a Bonferoni-corrected cutoff p value of 0.025 (0.05/2 hemispheres) revealed significant FA reduction of both hemispheres in the schizophrenia compared with HC.

d

A two sample t-test with a Bonferoni-corrected cutoff p value of 0.006 (0.05/8 regions) showed significant FA reduction in the schizophrenia compared with the HC.

e

A two sample t-test showed trend level (p <0.05) FA reduction in the schizophrenia compared with the HC.