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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: Cancer Res. 2014 Apr 16;74(12):3369–3377. doi: 10.1158/0008-5472.CAN-13-3216

Figure 5. E2f1S29A/S29A mice display decreased NER efficiency.

Figure 5

(a) The dorsal skin of E2f1S29A/S29A and wild type sibling control mice were shaved and exposed once to 1,000 J/m2 of UVB. Genomic DNA was isolated from the exposed epidermis at the indicated time points and the amounts of 6-4PP (a) and CPD (b) were measured by ELISA using anti-6-4PP and anti-CPD antibodies, respectively. Two mice per genotype for each time point were used and each sample was subjected to ELISA in duplicate. *indicates statistical significance using 2 sample test for equality of proportions with continuity correction.