Table 1.
Gene mutations identified in serous borderline tumors by whole exome sequencing.
| Gene | Genbank | Mutation | AA Change | |
|---|---|---|---|---|
| Tumor SBT-s2 | BRAF | NM_004333.4 | c.1781A>G | D594G |
| TRIO | NM_007118.2 | c.8881C>T | P2961S | |
| FOXRED2 | NM_001102371.1 | c.1114G>A | M328I | |
| HRAS | NM_001130442.1 | c.182A>G | Q61R | |
| DST | NM_015548.4 | c.964A>G | I322V | |
| UBR2 | NM_001184801.1 | c.994C>T | R332C | |
| HAUS6 | NM_017645.3 | c.1108G>T | V370F | |
| AR | NM_000044.2 | c.1013C>A | T338K | |
| C2orf16 | NM_032266.3 | c.5223_5246del24 | H1742_R1749del | |
| PEAR1 | NM_001080471.1 | c.2512_2526del15 | P839_F843del | |
| Tumor SBT-s5 | BRAF | NM_004333.4 | c.1799T>A | V600E |
| NCCRP1 | NM_0010011414.1 | c.781C>T | R261W | |
| OXGR1 | NM_080818.3 | c.766C>T | P256S | |
| FBXW7 | NM_001013415.1 | c.1288C>T | Q430X | |
| STX19 | NM_001001850.2 | c.835C>A | P279T | |
| SLC24A5 | NM_205850.2 | c.832C>T | L278F | |
| KIAA1462 | NM_020848.2 | c.1620_1623del4 | Q542fsX35 |