Figure 9.

SRW-specific antibody. Mice were bled before the first immunization, immunized, and challenged intranasally with SRW as described in Methods, and then bled on days 6 and 13 during the protocol of sensitization, and again 48 hours (day 16) and 96 hours (day 18) after intranasal challenge. Levels of SRW-specific antibody were determined by ELISA. The points represent the concentration of antibody for individual mouse (n = 4 per group). Note the increase in IgG1 and IgG2b content in SRW-treated HLA-DQ6, but not H-2Aβ⁰, mice.