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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Semin Nephrol. 2013 Nov;33(6):557–564. doi: 10.1016/j.semnephrol.2013.08.006

Figure 5.

Figure 5

Plasma complement levels in 20 ANCA disease patients during active disease compared to remission. (a) Plasma C5b-9. (b) Plasma C5a. (c) Plasma C3a. (d) Plasma Bb. (e) Plasma properdin. (f) Plasma C4d. Plasma levels of C3a, C5a, C5b-9, and Bb were significantly higher in active disease than remission, whereas plasma properdin were significantly lower in active disease. These findings are consistent with alternative pathway complement activation during active ANCA disease. (Reprinted from Reference 22 with permission)