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125I–TNF-α tracer studies. (a) 125I–TNF-α was instilled with PA103, PA103ΔUT, or vehicle. The quantity of 125I–TNF-α in the circulation is shown as a percentage of the initial dose instilled into the airspaces. Mean ± SEM. *P < 0.05 vs. group instilled with airspace PA103. (b) Plasma concentration curves of intravenously injected 125I–TNF-α and 131I-albumin. Data are percentages of the peak values at 1 minute after the injection.
