Skip to main content
. 1999 Sep 15;104(6):709–719. doi: 10.1172/JCI7315

Figure 5.

Figure 5

Hemodynamic parameters during dobutamine dose response for NC and 10-week AC Fgf2+/+ and Fgf2–/– mice. *P < 0.05 vs. baseline. n = 5 for NC and AC Fgf2+/+ and Fgf2–/–. (a) LVP for NC and 10-week AC Fgf2+/+ and Fgf2–/– mice during dobutamine stimulation. Ten-week AC Fgf2+/+ and Fgf2–/– mice had similar increases in LVP. (b) SBP for NC and 10-week AC Fgf2+/+ and Fgf2–/– mice during dobutamine stimulation. Systemic SBP was decreased in 10-week AC mice. (c) +dP/dt for NC and 10-week AC Fgf2+/+ and Fgf2–/– mice during dobutamine stimulation. AC Fgf2–/– mice had a similar increase in the rate of contractility as NC mice during β-adrenergic stimulation; however, AC Fgf2+/+ had a blunted response to increasing dobutamine levels.