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Myocellular concentration of membrane and cytosolic DAGs and myocellular total ceramide concentrations (A) and activation of PKCθ, -δ, and -ε (B) in young lean healthy controls (CON) (white columns; n = 16), in young obese humans (OBE) (dark gray columns; n = 10), and in elderly obese patients with T2D (black column; n = 10). Data are given as means ± SEM. *P < 0.05; #P < 0.01; §P < 0.001.
