Table 2.
Cell line | Clones analyzed | Single excision | Biallelic excision without reintegration, no. of clones (frequency) | Biallelic excision with reintegration, no. of clones (frequency) |
T2-4 | 6 | 4 | 0 (0%) | 2 (33.3%) |
T1-6 | 11 | 6 | 2 (18%) | 2 (18%) |
Mean frequency | 9% | 25.7% |
T1, targeting clone used L540long-R560 TALEN pair; T2, targeting clone used L538-R557 TALEN pair.