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Immunostaining of E-cadherin (green) for epithelial cells cultured on pillar (A), pit (B) and flat (C) substrates. Nuclei are stained in red. The scale bars show 50 μm. The yellow lines outline the pillar or pit features. Panels A1 and B1 show the cross-sectional views (dotted pink and blue lines) of the images in panels A2 and B2. Panels a and b show merged enlargements of the corresponding boxed areas in panels A2 and B2.
