Table 1.
Growth ability of epithelial cells cultured for 48 h on micropatterned substrates with pillar and pit
|
Locational classification of convex or concave in vertical direction |
Pillar substrate |
Pit substrate |
||
|---|---|---|---|---|
| Ratio of increased cell number, X 48 / X 24 (-) | Ratio of dividing cells, R d (10 -2 ) | Ratio of increased cell number, X 48 / X 24 (-) | Ratio of dividing cells, R d (10 -2 ) | |
| RTA region |
1.8 ± 0.8 |
91.3 ± 7.3 |
1.8 ± 0.5 |
94.0 ± 3.9 |
| R1 region |
3.9 ± 1.8 |
90.9 ± 8.4 |
2.7 ± 1.4 |
89.2 ± 8.0 |
| R2 region |
1.4 ± 1.0 |
91.4 ± 7.1 |
1.5 ± 0.4 |
94.3 ± 5.6 |
| Flat Region | 2.1 ± 0.7 | 84.0 ± 8.4 | 2.6 ± 0.6 | 96.1 ± 2.1 |
Measurements were made in an individual 9 pillars and pits. Data are expressed as means ± standard deviation from triplicate measurements and analyzed using Student’s t-test. There were no statistically significant differences among the data sets.