. Author manuscript; available in PMC: 2015 Jan 1.

Published in final edited form as: J Nucl Med. 2013 Dec 12;55(1):23–29. doi: 10.2967/jnumed.113.122630

TABLE 3.

Estimated Radiation Doses for ⁶⁴Cu-DOTA-Trastuzumab ^*,^†

	Equivalent or effective dose per unit injected activity (mSv/MBq)	Equivalent or effective dose per PET examination (mSv)^‡
Heart wall	0.16	71
Kidneys	0.09	42
Liver	0.12	53
Red marrow	0.04	17
Spleen	0.10	45
Whole body	0.02	10

Effective dose	0.03	12

Trastuzumab protein dose = 50 mg.

^†

Calculations employed averaged time-activity curves (8 patients) from our ¹¹¹In-MxDTPA-trastuzumab study (7), which were normalized to averaged blood and organ uptake data from the current ⁶⁴Cu-DOTA-trastuzumab study (6 patients).

^‡

Assumes ⁶⁴Cu injected activity = 450 MBq, the average in the current study.