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. Author manuscript; available in PMC: 2014 Jul 7.
Published in final edited form as: Br J Ophthalmol. 2013 Jan 29;97(4):504–510. doi: 10.1136/bjophthalmol-2012-302650

Figure 2.

Figure 2

Systemic peptidoglycan (PGN) exposure does not predispose to uveitis. Onset and severity of ocular inflammation were monitored over a 72 h period after systemic exposure to PGN or saline as described above in figure 1. (A) The leukocyte trafficking response within the iris was measured by intravital videomicroscopy, and the number of rolling (left panel), adherent (middle panel) and infiltrating (right panel) cells was quantified, *p<0.05 comparison to saline controls within a genotype (n=10 mice/treatment/genotype/time). (B) and (C) are histological images of the anterior and posterior eye segments from a PGLYRP-2 knockout mouse obtained at 72 h post PGN injection (H&E stain, original magnification at 200 ×). C: cornea; I: iris; CB: ciliary body; L: lens; INL: inner nuclear layer; ONL: outer nuclear layer; H&E, haematoxylin and eosin.