Figure 1.
(a) Schematic of the functional domains of the TnT protein and the location of the I79N and R92Q mutations in the protein. (b) Western blot showing expression of the eTnT, R92Q, I79N, and aTnT protein products in HEK 293 cells infected with the recombinant adenoviral constructs AdCMVeTnT, AdCMVR92Q, AdCMVI79N, and AdCMVaTnT. The migration patterns (from top to bottom) of the embryonic isoform, a minor adult isoform, and the major adult isoform are shown next to the blot. Control is from adult rat heart.